If Heinrich manages to slow down Kyrie's offense like he did in the preseason game, this could be a blowout. But I think Kyrie will be eager to shake that performance of.
Andy - Noah will likely cancel each other out, Boozer's offensive edge will trump TT's defensive edge, Deng will be more than a handful for Gee on both sides of the floor and I'm curious to see how Dion matches up against a wily veteran like Rip.
The Bulls bench is quite experienced and potent, unlike ours.
If we can keep this competitive until the 4th quarter we will have a chance and that will only happen if Kyrie will have a good game. It will be interesting, since this is a much more serious test than the depleted Wizards.