If Brennan and/or Freeman are able to demonstrate OBP ability then sure, they can hit in the 2 hole. However it is difficult to do that through contact alone, and will require a combination of power and discipline. Brennan would've been the most aggressive chaser in all of MLB in his limited sample and Freeman has yet to show any pop or walk drawing ability. Otherwise you're basically just replacing Amed with Amed. You could lump Rocchio into this too who probably projects to be a similar hitter in the future.
I like the Amed/Brennan/Freeman profile a lot more in the 3 hole personally. If guys get on then they're there to hit them in. If the top 2 guys get out then well who cares, 2 outs and nobody on is low leverage.